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Human tissue studies should improve stroke care

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Human tissue studies should improve stroke care

Scientists who are studying slices of living brain tissue believe that their research could eventually lead to new stroke therapies.

A team at the Medical College of Georgia is using brain tissue to discover which drugs can block the after-effects of stroke, which occur when the brain is starved of blood and oxygen.

Around one fifth of the body's energy is required by the brain, and around half of that is used to help ensure that brain cells have the required levels of sodium and potassium.

After a stroke, however, these pumps need to start working again quickly to prevent brain cell death and researchers are looking for drugs that aid this process.

Neuroscientist Dr Sergei Kirov, who directs the college's Human Brain Laboratory, revealed: "We only have one approved drug therapy for stroke and new approaches are needed to improve treatment for the third leading cause of death in western countries."

He added that slices of human brain tissue can provide a "missing link" between animals and humans for research purposes, offering a "unique chance to identify and study potentially useful therapeutics".

Around 150,000 people in the UK have a stroke every year, highlighting the need to find new drugs that will improve stroke care.

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Human tissue studies should improve stroke care